After being bitten by a genetically-modified spider, a shy teenager gains spider-like abilities that he uses to fight injustice as a masked superhero and face a vengeful enemy.
On a school field trip, Peter Parker (Maguire) is bitten by a genetically modified spider. He wakes up the next morning with incredible powers. After witnessing the death of his uncle (Robertson), Parkers decides to put his new skills to use in order to rid the city of evil, but someone else has other plans. The Green Goblin (Dafoe) sees Spider-Man as a threat and must dispose of him. Even if it means the Goblin has to target Parker's Aunt (Harris) and the girl he secretly pines for (Dunst)